 Structural basis of complement membrane attack complex formation by Marina Serna and others

Nature Communications7,10587(2016); DOI10.1038/ncomms10587. Full primary byline Marina Serna, Joanna L.Giles, B.Paul Morgan, Doryen Bubeck verified. Results: Cryo-EM structure of the MAC; Molecular architecture; Auxiliary domains and MAC assembly; Figure1. Pores assembled on liposomes, functional dye-release check, detergent isolation, frozen-hydrated imaging with direct-electron detection. Reconstructed end product contains18 C9 copies; do not treat this as a universal minimum for lysis.