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1Basic local alignment search tool by Stephen F. Altschul and othersbasic-local-alignment-search-tool-by-stephen-f-altschul-and-others2026-10-202026-10-20
1Improved tools for biological sequence comparison by William R. Pearson and David J. Lipmanimproved-tools-for-biological-sequence-comparison-by-william-r-pearson-and-david-j-lipman2026-10-202026-10-20
1The statistics of sequence similarity scores by National Center for Biotechnology Informationthe-statistics-of-sequence-similarity-scores-by-national-center-for-biotechnology-information2026-10-202026-10-20
1Multiplex genome engineering using CRISPR/Cas systems by Le Cong and othersmultiplex-genome-engineering-using-crispr-cas-systems-by-le-cong-and-others2026-10-202026-10-20
1CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes by Luke A. Gilbert and otherscrispr-mediated-modular-rna-guided-regulation-of-transcription-in-eukaryotes-by-luke-a-gilbert-and-others2026-10-202026-10-20
1Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia by R. K. Saiki and othersenzymatic-amplification-of-beta-globin-genomic-sequences-and-restriction-site-analysis-for-diagnosis-of-sickle-cell-anemia-by-r-k-saiki-and-others2026-10-202026-10-20
1Involvement of the central loop of the lactose permease of Escherichia coli in its allosteric regulation by the glucose-specific enzyme IIA of the phosphoenolpyruvate-dependent phosphotransferase system by C. Hoischen and othersinvolvement-of-the-central-loop-of-the-lactose-permease-of-escherichia-coli-in-its-allosteric-regulation-by-the-glucose-specific-enzyme-iia-of-the-phosphoenolpyruvate-dependent-phosphotransferase-system-by-c-hoischen-and-others2026-10-202026-10-20
1The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution by T. Kawashima and othersthe-structure-of-the-escherichia-coli-ef-tu-ef-ts-complex-at-2-5-a-resolution-by-t-kawashima-and-others2026-10-202026-10-20
1Structure of Subtilisin BPN′ at 2.5 Å Resolution by C. S. Wright and othersstructure-of-subtilisin-bpn′-at-2-5-a-resolution-by-c-s-wright-and-others2026-10-202026-10-20
1Catalytic antibodies by Alfonso Tramontano and otherscatalytic-antibodies-by-alfonso-tramontano-and-others2026-10-202026-10-20
1Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane by S. W. Cushman and otherspotential-mechanism-of-insulin-action-on-glucose-transport-in-the-isolated-rat-adipose-cell-apparent-translocation-of-intracellular-transport-systems-to-the-plasma-membrane-by-s-w-cushman-and-others2026-10-202026-10-20
1Reconstitution of Purple Membrane Vesicles Catalyzing Light-driven Proton Uptake and Adenosine Triphosphate Formation by Efraim Racker and othersreconstitution-of-purple-membrane-vesicles-catalyzing-light-driven-proton-uptake-and-adenosine-triphosphate-formation-by-efraim-racker-and-others2026-10-202026-10-20
1ATP formation caused by acid-base transition of spinach chloroplasts by A. T. Jagendorf and othersatp-formation-caused-by-acid-base-transition-of-spinach-chloroplasts-by-a-t-jagendorf-and-others2026-10-202026-10-20
1Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells by Brian J. Druker and otherseffects-of-a-selective-inhibitor-of-the-abl-tyrosine-kinase-on-the-growth-of-bcr-abl-positive-cells-by-brian-j-druker-and-others2026-10-202026-10-20
1ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase by D. M. Gill and othersadp-ribosylation-of-membrane-proteins-catalyzed-by-cholera-toxin-basis-of-the-activation-of-adenylate-cyclase-by-d-m-gill-and-others2026-10-202026-10-20
1Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours by L. A. Donehower and othersmice-deficient-for-p53-are-developmentally-normal-but-susceptible-to-spontaneous-tumours-by-l-a-donehower-and-others2026-10-202026-10-20
1Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system by Rolf M. Zinkernagel and othersrestriction-of-in-vitro-t-cell-mediated-cytotoxicity-in-lymphocytic-choriomeningitis-within-a-syngeneic-or-semiallogeneic-system-by-rolf-m-zinkernagel-and-others2026-10-202026-10-20
1Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching by Lawrence K. Lee and othersstructure-of-the-torque-ring-of-the-flagellar-motor-and-the-molecular-basis-for-rotational-switching-by-lawrence-k-lee-and-others2026-10-202026-10-20
1Selecting One of Several Mating Types through Gene Segment Joining and Deletion in Tetrahymena thermophila by Marcella D. Cervantes and othersselecting-one-of-several-mating-types-through-gene-segment-joining-and-deletion-in-tetrahymena-thermophila-by-marcella-d-cervantes-and-others2026-10-202026-10-20
1Genome-defence small RNAs exapted for epigenetic mating-type inheritance by Deepankar Pratap Singh and othersgenome-defence-small-rnas-exapted-for-epigenetic-mating-type-inheritance-by-deepankar-pratap-singh-and-others2026-10-202026-10-20

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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