Ciro Santilli @cirosantilli  40

One of the very few encrypted emails... beauty. And they also have an encrypted password manager!!! Using this is a must as of 2023 basically. The only missing thing now is to find a fully open source alternative!!!

Sure, search capabilities have to be somewhat limited: proton.me/blog/engineering-message-content-search

techcrunch.com/2021/09/06/protonmail-logged-ip-address-of-french-activist-after-order-by-swiss-authorities/ you've fucking got to use Tor Browser with it if you want your IP to remain hidden, learn that...

Their backend is closed source: www.reddit.com/r/ProtonMail/comments/iyjqxf/is_protonmails_backend_open_source/

Are daily notifications without a recovery email possible? www.reddit.com/r/ProtonMail/comments/yjau8f/allow_daily_email_notifications_without_having_a/ OK, they do work actually.

The lack of Gmail dot trick is tragic however, and you have to pay for multiple aliases. But you can however create separate inboxes with the same cell phone verification however.

Bibliography:

This is the easiest one to do iteratively:

This is the hardest one to do iteratively.

Bibliography:

Overview by Ciro Santilli at: superuser.com/questions/284342/what-are-path-and-other-environment-variables-and-how-can-i-set-or-use-them/1864687#1864687

Listed at: pubs.opengroup.org/onlinepubs/9699919799/utilities/contents.htm

If you are a programmer, grep becomes a verb: "to grep" means "to search text files", much like "to Google" means "to search random stuff online".

PNG reference implementation. Ahh, if feels good to have a dominating open source reference implementation.

Demo of using it by Ciro Santilli: stackoverflow.com/questions/1362945/how-to-decode-a-png-image-to-raw-bytes-from-c-code-with-libpng/36399711#36399711

Also known as: Quantitative PCR (qPCR).

Like PCR, but the amplification machine measures the concentration of DNA at each step.

This describes one possible concentration detection method with fluorescent molecules that only become fluorescent when the DNA is double stranded (SYBR Green)

This allows you to predict the exact initial concentration by extrapolating the exponential curve backwards.

TODO: vs non-real-time PCR. Why can't you just divide by 2 for every heating step to reach back the original concentration? Likely the reaction reach saturation at an unknown step.

TODO: vs non-real-time PCR in medical diagnostics: do you really need to know concentration for diagnostics? Isn't it enough to know if the virus is present or not?

Isothermal means "at fixed temperature".

This is to contrast with the more well established polymerase chain reaction, which requires heating and cooling the sample several times.

The obvious advantage of isothermal methods is that their machinery can be simpler and cheaper, and the process can happen faster, since you don't have to do through heating and cooling cycles.

E.g. showing live data from a scientific instrument! TODO:

By Ciro Santilli.

It does a huge percentage of what you want easily, and from the language that you want to use.

Tends to be Ciro's pick if gnuplot can't handle the use case, or if the project is really really serious.

Couldn't handle exploration of large datasets though: Survey of open source interactive plotting software with a 10 million point scatter plot benchmark by Ciro Santilli

Examples:

Tested on Python 3.10.4, Ubuntu 22.04.

Tends to be Ciro Santilli's first attempt for quick and dirty graphing: github.com/cirosantilli/gnuplot-cheat.

domain-specific language. When it get the jobs done, it is in 3 lines and it feels great.

When it doesn't, you Google for an hours, and then you give up in frustration, and fall back to Matplotlib.

Couldn't handle exploration of large datasets though: Survey of open source interactive plotting software with a 10 million point scatter plot benchmark by Ciro Santilli

This game (1 or 2, can't remember) made an impression on Ciro Santilli for some reason.

Only many many years after playing it, after Ciro started getting more interested, did he learn that it was actually an adaptation of the Chinese mega-classic Water Margin.

"Suikoden" is the actual Japenese transliteration for the Chinese name of the original Water Margin novel.

Yet another case of Chinese thing better known in the West as Japanese.

The game puts great emphasis on the concept of the 108 Stars of Destiny, which never left Ciro's mind: making 108 allies, the main collectible of the game, allows you to make a more powerful alliance, and unlock better endings.