= A. Malmström
{c}
<A. Malmström> coauthored, with <L. Åberg>, a 1982 assay for the <chondroitin-glucuronate 5-epimerase> activity involved in <dermatan sulfate> biosynthesis. The reaction changes the stereochemical configuration of sugar residues already attached to a <polysaccharide>, rather than synthesizing a free sugar first.<Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase by A. Malmström and L. Åberg>[Original byline and Abstract: polymer-level reaction]{ref}
The experiment used <chondroitin> carrying <tritium> at the reacting carbon. Release of the label during incubation was measured with a <scintillation counter>, converting a hard-to-see molecular exchange into a countable assay signal.<Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase by A. Malmström and L. Åberg>[Abstract: labelled substrate, distillation and liquid-scintillation counting]{ref}
The preparations also distinguished activities associated with <dermatan sulfate> and <heparan sulfate> biosynthesis through different requirements for <pH> and cofactors. Similar overall <epimerization> chemistry therefore did not establish that the same <enzyme> performed both biological tasks.<Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase by A. Malmström and L. Åberg>[Abstract: two microsomal epimerase activities]{ref}
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