Bacillus virus phi29 2026-10-24
A double-stranded DNA bacteriophage of Bacillus subtilis, widely discussed as a model of active genome packaging. A portal-associated molecular motor uses ATP hydrolysis to oppose the physical costs of dense DNA confinement.[ref]
This original single-molecule study, with Thorsten Hugel among its authors, identifies the Bacillus subtilis host in its introduction and tests a proposed packaging-motor motion. The host statement corrects the organism mismatch in the Oxford 2021 examination.
The named bacteriophage, Bacillus virus phi29, infects Bacillus subtilis; the paper's identification of Escherichia coli as its host is incorrect. This correction does not alter the idealized geometry or numerical inputs used below.[ref]