Bub3 (source code)

= Bub3
{c}

A checkpoint component participating in kinetochore-associated signalling and <mitotic checkpoint complexes>.

Its binding interactions help localize checkpoint machinery and assemble inhibitory signals that delay anaphase when attachment is inadequate. A checkpoint component is therefore part of a communication system between <chromosome> attachment state and cell-cycle progression. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 17, The Spindle Assembly Checkpoint]{ref}