TBX2 Created 2026-10-20 Updated 2026-11-05
TBX2 is a T-box transcription factor involved in developmental control of cellular identity and proliferation. In the developing heart, it contributes to regional gene programmes that distinguish specialized territories from chamber myocardium. It is related to TBX3 but the two factors are not interchangeable in every context. Shared DNA-binding-family membership therefore does not establish identical expression or developmental function. [ref]