A transcription factor is a protein that regulates transcription. Combinations of transcription factors help select gene expression patterns during cell differentiation. [ref]
Anatomy and Physiology 2e by J. Gordon Betts and others. Anatomy and Physiology 2e, §3.6, Differentiation and Figure 3.35: transcription factors
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Transcription factors are proteins that play a crucial role in the regulation of gene expression. They bind to specific sequences of DNA near the genes they regulate, thereby influencing the transcription of those genes by either promoting or inhibiting the recruitment of RNA polymerase, the enzyme responsible for synthesizing RNA from a DNA template. Transcription factors can act as activators or repressors.