By Erez Lieberman.
Verified locator: Science 326 (2009), 289–293; DOI 10.1126/science.1181369. Figure 1, Hi-C crosslinking/digestion/end labeling/ligation workflow, and results on chromosome territories and compartments. Published first-author name Erez Lieberman-Aiden; author-lab publication list connects the earlier Erez Lieberman byline.
Erez Lieberman 2026-11-05
Erez Lieberman is an author of the 2007 language-evolution paper. The Aiden laboratory publication list records that paper under this byline and later work under Erez Lieberman Aiden, the name used on his author website.[ref]
https://aidenlab.org/publications.html. 2007 publication and subsequent author records
[ref]His work includes developing Hi-C, a method for measuring large-scale spatial relationships within genomes. The original 2009 study chemically fixed chromatin contacts, digested the DNA, marked fragment ends and ligated nearby ends. Sequencing the joined fragments yielded pairs of genomic positions whose contact frequencies could be compared.[ref]
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome by Erez Lieberman-Aiden and others. Figure 1 and experimental workflow
The resulting contact map is a population-level measurement, not a literal photograph of one chromosome's shape. The study tested features such as preferential contacts within the same chromosome and large-scale compartmentalization. A contact count reflects experimental recovery as well as physical proximity, so interpretation depends on normalization and the assay's sampling process.[ref]
Erez Lieberman Aiden, portrait identified by Rice University
. Portrait source: profiles.rice.edu/faculty/erez-lieberman-aiden .
Language change 2026-11-05
Language change is systematic change over time in a community's sounds, grammatical patterns or meanings. It can be investigated by comparing historical records or repeated measurements, while separating change from differences in sampling, spelling and individual style. A text corpus supplies observations rather than a complete record of every speaker.
A 2007 study by Erez Lieberman and collaborators tracked 177 verbs irregular in Old English. In their dataset, 145 remained irregular at the Middle English stage and 98 at the modern endpoint. Their statistical model related the rate of verb regularization to usage frequency, with estimated half-life proportional to the square root of frequency.[ref]
Quantifying the evolutionary dynamics of language by Erez Lieberman and others. Abstract; Methods Summary; Fig. 1 and Table 1
Under that fitted scaling, a 100-fold frequency increase predicts a tenfold half-life increase. This is an empirical relationship for the studied process and data, rather than a universal law for every kind of language change. The historical endpoint must not be mistaken for a fresh count of present-day usage.
Verb regularization 2026-11-05
Verb regularization is a form of language change in which an exceptional verb form is replaced by one following a productive grammatical pattern. For English past forms, this can mean adopting the
-ed pattern rather than retaining an inherited alternative. Historical change in a speech community is distinct from a child's occasional application of a pattern to an irregular verb.A quantitative study by Erez Lieberman and collaborators tracked irregular verbs across historical stages and identified
help among verbs that became regular.[ref]Quantifying the evolutionary dynamics of language by Erez Lieberman and others. opening discussion and Fig.1, historical examples and usage-frequency bins
A hypothetical series with regular forms in 12 of 40 past-tense uses at one stage and 32 of 40 at another would show the regular variant's proportion rising from to . Those counts alone would not establish the cause: recording practices, speaker composition and competing variants must also be checked. Regularization describes a pattern of inflection, not a judgment that the newer form is intrinsically better.