FGFR2 (source code)

= FGFR2
{c}

<FGFR2> is a <receptor> <tyrosine> kinase in the <fibroblast> growth factor <receptor> family. Ligand-dependent activation connects an extracellular signal to intracellular <phosphorylation> pathways that influence development and cellular behaviour. Alternative <receptor> isoforms differ in <ligand> recognition; <FGF10> is a <ligand> for the epithelial FGFR2b isoform. Thus expression of the generic <receptor> name alone does not specify every <ligand> response. <FGF receptor family by the IUPHAR-BPS Guide to Pharmacology>[IUPHAR/BPS, FGF receptor family: FGFR2 ligands and isoforms]{ref}