Haplotype estimation
= Haplotype estimation
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<Haplotype estimation> reconstructs which <alleles> share a <chromosome> from observed <genotypes> and other information, such as <pedigrees>. A doubly <heterozygous> <genotype> can be $AB/ab$ or $Ab/aB$; a <phase-known genotype> distinguishes them. Uncertainty in that reconstruction must propagate to estimated <haplotype frequencies> and <linkage disequilibrium>.