= Histone demethylase
An <enzyme> that removes particular <histone> methyl marks.
Different demethylases act on different residues and methylation states, so removal of <H3K4 methylation> and removal of <H3K27 trimethylation> are distinct activities. Regulated removal makes a <chromatin> mark reversible without requiring replacement of the underlying <DNA> sequence. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}
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