METTL3 (source code)

= METTL3
{c}

<METTL3> is a catalytic component of a <protein> complex that deposits N6-methyladenosine on <RNA>, especially messenger <RNA>. It works with METTL14 and regulatory components rather than determining every cellular methylation site in isolation. Modification can affect <RNA> processing, stability or <biological translation> through <proteins> that recognize the mark. The effect of a <METTL3> perturbation therefore depends on which transcripts and readers are present. <UniProtKB by the UniProt Consortium>[Q86U44, Function, Catalytic activity and Subunit structure]{ref}