Let . The Markov jump-process generator applied to gives the exact moment equation . With the prescribed moment closure, , stationarity gives
The production flux counts molecules, not reaction events: it is , while the removal flux is . The reaction-rate elasticity of removal relative to constant production is
The mean molecular lifetime is population divided by its stationary molecular removal flux. Therefore
The noise-relevant average chemical event size is the molecular-flux-weighted reaction event size. For the stoichiometric vectors and it is
This weights each absolute jump by the molecular turnover it contributes. Equivalently, the balanced production and removal fluxes give equal weight to their sizes and , yielding . An event-count-weighted average would be , since three quarters of firing events are deaths at stationarity; that different average does not determine the diffusion term in the linear noise approximation.
For , symmetry of the unique stationary mean-field state gives and the balance . The fraction of the molecular removal flux using the joint reaction and the mean molecular lifetime are consequently
In particular , , and .
The total loss flux of species one is , whereas its production flux is constant. The reaction-rate elasticities are therefore and at the symmetric state. Species two gives , . All chemical jumps in either component have unit absolute size, so their molecular-flux-weighted reaction event sizes satisfy . With , this proves
The same matrix follows from with and the drift Jacobian matrix in part (b); its positive eigenvalues are the restoring rates.
For the chemical diffusion matrix, each component receives noise from one unit birth, its own unit death, and the joint unit loss. The unnormalized diagonal noise intensity is
Only the joint reaction changes both components in one event. Its stoichiometric vector is , so . The positive sign reflects simultaneous decreases, rather than independent death events. Divide by the product of the means to normalize:
Thus the chemical diffusion matrix in the normalized stationary fluctuation-dissipation relation for a reaction network is
The unequal roles of and matter: describes restoration of perturbations, while records the covariance of the immediate stochastic reaction increments.