= Nucleotide-binding leucine-rich repeat receptor
= NLR
{c}
{synonym}
A <nucleotide-binding leucine-rich repeat receptor>, or <NLR>, is an intracellular immune-receptor <protein> characterized by a nucleotide-binding region and leucine-rich repeats. In <plants>, <NLRs> can detect pathogen-associated <molecules> or their effects and initiate defensive signaling.
An <NLR> can work as a sensor, a signaling helper or part of a <paired NLR> system. Different individuals can carry different <receptor> inventories, so one <reference genome> does not fully describe the species-wide <pan-NLRome>.<A species-wide inventory of NLR genes and alleles in Arabidopsis thaliana by Anna-Lena Van de Weyer and others>[2019, species-wide inventory]{ref}
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