Ole Storstein (source code)

= Ole Storstein
{c}

\b[<Ole Storstein>] is first author of a 1959 experimental study separating <airway resistance> from <lung compliance>. The investigators recorded mouth-to-esophageal pressure differences, breathing volume and <airflow> to analyze the mechanical behavior of respiration.<Airway Resistance and Lung Compliance by Ole Storstein and others>[Primary byline; Methods, simultaneous pressure, volume and airflow recordings]{ref}

The apparatus used an intra-esophageal balloon, a differential <pressure transducer> and a <pneumotachograph> with volume integration. The paper selected corresponding points of no mouth airflow for its compliance calculation and used paired observations during inflation and deflation to estimate resistance.<Airway Resistance and Lung Compliance by Ole Storstein and others>[Methods, Sanborn recording apparatus and definitions of compliance and resistance]{ref} Simultaneous signals matter because a pressure observed during flow includes a different mechanical contribution from pressure observed after that flow term vanishes.

For an original one-compartment model with a chosen zero-volume baseline, write
$$
P(t)=\frac{V(t)}{C}+R\dot V(t),
$$
where $C$ is <lung compliance> and $R$ is <airway resistance>. This neglects inertial and regional effects. At stipulated $C=0.10\,\mathrm{L}/(\mathrm{cm\ H_2O})$, $V=0.40$ L, $R=5\,\mathrm{cm\ H_2O\,s/L}$ and $\dot V=0.20$ L/s, the elastic contribution is 4 and the resistive contribution is 1 cm of water. Total modeled pressure is 5 cm of water.

Dividing volume by that total would give $0.08\,\mathrm{L}/(\mathrm{cm\ H_2O})$, below the chosen compliance. At the same modeled volume and zero flow, pressure becomes 4 cm of water and the ratio recovers 0.10. A time point and the definition of the pressure difference are therefore part of the observable, rather than optional details.

The primary paper explicitly notes the limitation of treating a nonuniform mechanical system as uniform.<Airway Resistance and Lung Compliance by Ole Storstein and others>[Discussion, interpretation of the simplified mechanical analysis]{ref} Zero net airflow at the mouth need not establish that every region has identical local behavior. Storstein's documented contribution combines apparatus, simultaneous observations and a stated mechanical interpretation, rather than equating one pressure/volume ratio with every aspect of lung function.