Let and be the potential outcomes for the same individual under well-defined interventions setting the binary exposure to 1 and 0. The average treatment effect, also called the average causal effect on the additive scale, is
The average is over the target population. This compares hypothetical outcomes under two interventions, rather than the observed difference , which can be distorted by confounding. For binary , the displayed contrast is a causal risk difference. Consistency in causal inference and a well-defined intervention, including an appropriate no-interference in causal inference assumption, give these potential outcomes their meaning.

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