Treat the BRST transformation as an odd graded derivation. In matrix notation the first three transformations are
Then
after substituting and using the Jacobi identity. Similarly, the two terms in
cancel because the ghost components anticommute and only the Lie-algebra commutator survives. Applying once more to gives a sum proportional to , which vanishes by Jacobi. Finally,
Thus on every field.
The gauge-invariant Yang-Mills and matter part is BRST invariant because a BRST variation is a gauge transformation with ghost-valued parameter. For the gauge-fixing fermion
the graded Leibniz rule gives
up to the common sign convention used to define the ghost term. This is precisely the gauge-fixing, auxiliary-field, and ghost sector of the displayed Lagrangian. Therefore
Under , the transition amplitude changes to first order by an insertion
If
with the corresponding condition on the bra, the two terms vanish after moving to the external states. The amplitude is then independent of the gauge-fixing choice.
Conversely, invariance for arbitrary changes of the gauge-fixing fermion requires physical external states to be BRST closed. States differing by a BRST-exact state have identical matrix elements against closed states, so the physical state space is the cohomology

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