For any observable , the Markov jump-process generator identity givesSet and . With , reaction 2 changes by and reaction 3 changes it by . Thereforeand, using and ,The equation for the second moment contains the third, whose equation contains the fourth, and so on. This is an infinite moment hierarchy.
Reaction 1 eventually leaves the odd initial copy number at . PutThe stationary first-moment equation givesThe stationary second-moment equation then givesUnder the prescribed central-moment closure,Substitution yields the requested polynomial equationThis cubic comes from the closure approximation; it is not an exact equation for the stationary mean.
Reaction 4 creates , reaction 5 removes one and one , and reaction 6 creates ; reaction 7 leaves unchanged. The exact first-moment equations are thereforeAt the assumed unique stationary distribution, both left-hand sides vanish. Eliminating the common mixed moment givesNo moment closure or independence assumption is involved.
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