Rabin8 (source code)
= Rabin8
{c}
<Rabin8> is a guanine-nucleotide exchange factor that activates <Rab8a> by promoting exchange of bound <GDP> for <GTP>. It links upstream trafficking signals to a Rab-controlled membrane-delivery pathway, including ciliary membrane formation. Its role is distinct from a GTPase-activating <protein>, which accelerates <GTP> <hydrolysis>. The exchange factor changes the state of the molecular switch rather than carrying all cargo itself. <NCBI Gene by the National Library of Medicine>[Homo sapiens, RAB3IP record, Summary and linked functional evidence]{ref}
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