Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system by Rolf M. Zinkernagel and others Created 2026-10-20 Updated 2026-10-31
Primary research: www.nature.com/articles/248701a0
Cited passages: Zinkernagel and Doherty, 1974, pp. 701–702, infected-target cytotoxicity across histocompatibility combinations.
Rolf M. Zinkernagel Created 2026-10-20 Updated 2026-11-05
Immunologist whose experiments helped establish MHC restriction. Zinkernagel and collaborators tested T-cell-mediated killing in viral infection, showing that recognition depends on the target’s compatibility with the responding immune cells.[ref]
Portrait of Rolf M. Zinkernagel
. Aasemsj; cropped by Wabbuh. CC BY-SA 3.0, via Wikimedia Commons. Source..jpg?width=260)