= Stefan Meyer
{disambiguate=mass spectrometry researcher}
{c}
\b[Stefan Meyer], the mass-spectrometry researcher identified by the 2017 paper below, developed automated analysis of <time-of-flight mass spectrometry> data with collaborators. The paper lists his affiliation with Space Research and Planetary Sciences at the University of Bern. Its motivation includes handling large numbers of measurements for chemical-composition studies in space instrumentation.<Fully automatic and precise data analysis developed for time-of-flight mass spectrometry by Stefan Meyer and others>[p.580, full byline, affiliation and Abstract]{ref}
The analysis connects sampled waveforms to mass-related quantities rather than treating every peak position as a known species. Its <instrument calibration> model relates the flight time $t$ to <mass-to-charge ratio> through
$$
\frac mz=k_0(t-t_0)^2,
$$
with instrument-dependent constants $k_0$ and $t_0$. Identified isotopes provide reference points for fitting the time-to-mass scale.<Fully automatic and precise data analysis developed for time-of-flight mass spectrometry by Stefan Meyer and others>[p.582, equation(2) and calibration paragraph]{ref}
For an original sensitivity calculation, suppose the corrected flight time is $t-t_0=20\,\mu\mathrm{s}$ and a timing displacement of $0.02\,\mu\mathrm{s}$ is introduced while the fitted constants are held fixed. The inferred ratio changes by
$$
\frac{(20.02)^2}{20^2}-1=0.002001,
$$
or $0.2001\%$. A0.1-percent timing change therefore produces about a0.2-percent change in this modeled mass-to-charge value. This is a consequence of the square law, not the paper's measured accuracy for an instrument.
The same study also describes integrating peak areas for quantitative analysis. Converting time to a mass scale, estimating an integrated signal and identifying a species are different analysis tasks; automation must keep their assumptions and reference data explicit.<Fully automatic and precise data analysis developed for time-of-flight mass spectrometry by Stefan Meyer and others>[p.582, Peak area determination, equation(3)]{ref}
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