Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride by Qingpin Xiao and others
= Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride by Qingpin Xiao and others
{c}
{tag=Work by Qingpin Xiao}
{title2=2020}
{title2=10.1038/s41467-020-19249-z}
https://doi.org/10.1038/s41467-020-19249-z
Nature Communications 11, 5430. The NADP–dihydrofinasteride structure, mutant assays and modeled <testosterone> placement provide complementary evidence; a trapped inhibitor is not a directly observed <testosterone> transition state.