Symmetric-group involution class-size collision ($n!/[2^{k}k!(n-2k)!]=\left(\genfrac{}{}{0ex}{}{n}{2}\right)⟺k=1\text{ or }(n,k)=(6,3)$)

A permutation of order two is a product of $k$ disjoint transpositions. Its conjugacy class has the displayed size. For $k\ge 2$, equality with the transposition class requires $(n-2)!/(n-2k)!=2^{k-1}k!$. The left side grows strictly with $n$. At $n=2k$, its ratio to the right side is one only for $k=3$; at $k=2$ it jumps from below to above one between $n=4$ and $n=5$, and for $k\ge 4$ it is already greater than one. Thus degree six is the only possible exceptional degree for an group automorphism not preserving transpositions.