Structure of human foetal deoxyhaemoglobin by J. A. Frier and M. F. Perutz 2026-11-05
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Primary structure record 1FDH, DOI doi.org/10.2210/pdb1FDH/pdb ; human fetal deoxyhemoglobin, X-ray diffraction at 2.50 angstrom resolution, assembly A2B2 and alpha/gamma chain identities. Related primary citation: J. A. Frier and M. F. Perutz, Journal of Molecular Biology 112, 97–112 (1977), PMID 881729, DOI doi.org/10.1016/S0022-2836(77)80158-7 . The indexed publisher abstract discusses structural changes associated with lower fetal deoxyhemoglobin affinity for 2,3-diphosphoglycerate. Initials retained; no full-name or deposition-name identity inference.
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The crystal structure of human deoxyhaemoglobin at 1.74 A resolution by G. Fermi and others 2026-11-05
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Primary human structure record 4HHB, PDB DOI doi.org/10.2210/pdb4HHB/pdb . Related byline G. Fermi, M. F. Perutz, B. Shaanan and R. Fourme, Journal of Molecular Biology 175, 159–174 (1984), DOI doi.org/10.1016/0022-2836(84)90472-8 , PMID 6726807. Macromolecules and assembly identify two alpha and two beta chains. Primary abstract: 1.74 angstrom refinement using room-temperature synchrotron X-ray film data. Literal publication initials retained; Perutz Work tag uses the verified canonical person name.
Primary Abstract, pubmed.ncbi.nlm.nih.gov/6726807/ : independence of the reported local geometry from imposed restraints was tested by unrestrained refinement of the entire molecule, starting from modified haem geometry. This is the specific model-sensitivity test cited in the G. Fermi profile.
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