 Armitage–Doll multistage model of carcinogenesis

The Armitage–Doll multistage model of carcinogenesis is a theoretical framework developed by British statisticians Sir Richard Doll and Sir Austin Bradford Hill in the 1950s. This model aims to describe the process through which cancer develops in an organism, specifically emphasizing that cancer is not the result of a single event but rather a series of cumulative genetic changes or mutations.