 Conformational proofreading

Conformational proofreading is a biological mechanism that enhances the accuracy of molecular processes, particularly in the context of protein synthesis and DNA replication. This concept is primarily relevant in the field of molecular biology and biochemistry, where it refers to the ability of an enzyme or molecular machinery to select the correct substrate or nucleotide during a reaction, minimizing errors. In the case of protein synthesis, for example, conformational proofreading occurs during the process of translation.