 G protein-gated ion channel

G protein-gated ion channels are a class of ion channels that are regulated by G proteins, which are intracellular signaling molecules that are activated by various types of receptors, typically G protein-coupled receptors (GPCRs). When a ligand (such as a neurotransmitter or hormone) binds to a GPCR, it activates the associated G protein by exchanging GDP for GTP.