 Paper spray ionization

Paper spray ionization is a novel mass spectrometry technique used for the direct analysis of various types of samples, including biological fluids, pharmaceuticals, and environmental samples. It is particularly advantageous for its simplicity, speed, and the ability to analyze samples with minimal preparation. In this method, a piece of absorbent paper is used as the substrate for the sample. Here’s how the process generally works: 1. **Sample Application**: The sample is applied onto the surface of the paper.