PICO is an acronym used to help formulate clinical research questions and guide the search for evidence in evidence-based practice. It stands for: - **P**atient or Problem: This refers to the specific patient group or condition being studied. - **I**ntervention: This is the treatment, intervention, or exposure being investigated. - **C**omparison: This involves the comparator or alternative intervention, which could be a placebo, standard treatment, or different intervention.
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