A "random coil" refers to a conformation of a polymer chain, particularly in the context of proteins and other macromolecules. In this state, the individual segments of the chain do not adopt a fixed or regular three-dimensional structure, resulting in a highly flexible, disordered configuration. This contrasts with more structured conformations like alpha helices and beta sheets, which are stable, ordered structures found in proteins. Random coils can be important in various biological and physical processes.
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