 Secondary electrospray ionization

Secondary electrospray ionization (SESI) is a mass spectrometry ionization technique that is used to analyze volatile and semi-volatile compounds in the gas phase. It is an extension of the conventional electrospray ionization (ESI) method, which is typically utilized for non-volatile compounds in solution. In SESI, a sample can be introduced as a gas or vapor rather than in a liquid form, which broadens the range of analytes that can be studied.