 Transverse relaxation-optimized spectroscopy

Transverse Relaxation-Optimized Spectroscopy (TROSY) is a technique used in nuclear magnetic resonance (NMR) spectroscopy that helps improve the sensitivity and resolution of signals from macromolecules, particularly large proteins and protein complexes. In NMR, the relaxation of the magnetic moments of nuclei can lead to signal loss over time, especially in large molecules where relaxation times can be significantly longer due to internal motion.