Amniote Updated 2025-07-16
Name origin: amnion, a pellicle that covers embryos of both eggs and also during pregnancy.
Includes:
Does not include amphibians. If you include them, you have the tetrapods.
Bat Updated 2025-07-16
As of 2020, account for about 20% of the known mammal species!!! www.sciencefocus.com/nature/why-are-there-so-many-species-of-bat/ mentions some reasons:
  • they can fly, so they can move out further
  • their eating habits are highly specialized
DNA methylation Updated 2025-07-16
The first found and most important known epigenetic marker.
Happens only on adenine and cytosine. Adenine methylation is much less common in mammal than cytosine methylation, when people say "methylation" they often mean just cytosine methylation.
It often happens on promoters, where it inhibits transcription.
Homeothermy Updated 2025-07-16
It is quite mind blowing that this is polyphyletic on mammals and birds, what can't parallel evolution achieve??
Figure 1.
Phylogenetic tree of the vertebrates
. Source. Highlights how birds should obviously be classified as reptiles.
Lysozyme Updated 2025-07-16
Breaks up peptidoglycan present in the bacterial cell wall, which is thicker in Gram-positive bacteria, which is what this enzyme seems to target.
Part of the inate immune system.
It is present on basically everything that mammals and birds excrete, and it kills bacteria, both of which are reasons why it was discovered relatively early on.
Marsupial Updated 2025-07-16
They split up from the rest of the mammals after the monotremes.
Every other mammal has a placenta.
This baby in pouch thing just feels like a pre-placenta stage.
Monotreme Updated 2025-07-16
The weirdest mammal clade: they lay fucking eggs. Only 5 known species alive as of 2020.
Eggs are basal: they simply didn't evolve out of what other reptiles do. From which we conclude that milk came before eggs stopped.
So this is the most basal subclade of mammals.
Etymology: means "single hole" in Greek, because like other reptiles it has a single hole for shit, pee and fucking: the cloaca.
Polyphyly Updated 2025-07-16
Basically mean that parallel evolution happened. Some cool ones:
Synapsid Updated 2025-07-16
Mammals and a bunch of extinct animals that look more like mammals than reptiles.
TODO name: Wikipedia says "being with a fused arch" but what does that mean???
Tetrapod Updated 2025-07-16
Includes:
The exact relationships between those clades is not very clear as there's a bunch of extinct species in the middle we are not sure exactly where they go exactly, some hypothesis are listed at: en.wikipedia.org/w/index.php?title=Tetrapod&oldid=1053601110#Temnospondyl_hypothesis_(TH)
But at least it seems rock solid that those three are actually clades.
X-inactivation Updated 2025-07-16
epigenetics mechanism.
Video 1.
X-Inactivation and Epigenetics by WEHImovies (2012)
Source. Shows how this makes every female mammal a chimera.