CD133, also known as Prominin-1, is a glycoprotein that is encoded by the PROM1 gene in humans. It is commonly used as a marker for identifying stem cells, particularly in hematopoietic (blood) and neural tissues. CD133 is a pentaspan membrane protein, which means it spans the cell membrane five times, and it is known to play a role in cell signaling and maintaining the stem cell phenotype.

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