In biochemistry, the control coefficient is a quantitative measure of how much a particular enzyme or step in a metabolic pathway influences the overall flux (rate of reaction) through that pathway. Control coefficients are essential for understanding metabolic regulation and how changes in the activity of specific enzymes can affect the overall metabolism of a cell or organism. The concept is rooted in the field of metabolic control analysis (MCA), which aims to quantify the control that different reactions have on the metabolic flux.
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