KCNK13, also known as TWIK-2 (Two-Pore domain potassium channel 2), is a gene that encodes a potassium channel protein in humans. It is part of the two-pore domain (K2P) potassium channel family, which is characterized by its unique structure and function. These channels play a vital role in maintaining the resting membrane potential of cells, regulating excitability, and controlling various physiological processes, including neuronal signaling, muscle contraction, and cardiac function.

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