Macromolecules are large, complex molecules that are essential for various biological functions. They are typically composed of thousands of atoms and include four primary types of biological macromolecules: 1. **Proteins**: These are made up of amino acids and play critical roles in biological processes, including catalyzing metabolic reactions (as enzymes), providing structural support, and regulating cellular functions. 2. **Nucleic Acids**: DNA and RNA are the two main types of nucleic acids.

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