Voltage-sensitive dyes (VSDs) are specialized fluorescent dyes that can be used to measure the electrical activity of membranes, particularly in neurons and other excitable cells. These dyes change their fluorescence properties in response to changes in membrane potential, allowing researchers to visualize and quantify electrical signals in real-time. ### Key Features of Voltage-Sensitive Dyes: 1. **Mechanism**: VSDs typically contain a hydrophobic moiety that embeds within the lipid bilayer of the cell membrane.
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