CheY is a bacterial response-regulator protein whose phosphorylation state couples receptor-pathway activity to bacterial flagellar motor behaviour. In Escherichia coli, CheA transfers phosphate to CheY, and phosphorylated CheY interacts with the motor switch, including FliM. CheZ accelerates signal removal through dephosphorylation. Production and removal therefore jointly control motor bias, allowing a biochemical pathway to regulate swimming without the motor directly sensing external attractant. [ref]
Robustness in simple biochemical networks by Naama Barkai and Stanislas Leibler. 1997, chemotaxis signalling and feedback architecture
New to topics? Read the docs here!