A clamped cubic spline is a cubic spline whose endpoint first derivatives are prescribed. A clamped cubic spline interpolant additionally matches prescribed values at its spline knots. Distinct spline knots, arbitrary nodal values and arbitrary endpoint slopes determine one such interpolant. The minimum roughness property of a clamped cubic spline proves uniqueness. Unlike the natural cubic spline, this construction prescribes endpoint slopes rather than zero endpoint second derivatives.
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