Hans Adolf Krebs developed the cyclic account of carbon oxidation now called the citric acid cycle. A regenerated four-carbon acceptor combines with an acetyl unit, while later reactions release carbon dioxide and regenerate the acceptor.
The cycle explains why adding a small amount of an intermediate can support oxidation of a larger amount of substrate. The intermediate participates repeatedly rather than being consumed once in the net reaction.[ref]
The citric acid cycle by Hans Adolf Krebs. 1953 lecture, pages 399–404 and Table 1
A biochemist.[ref]
https://www.nobelprize.org/nomination/archive/show.php?id=11165. Nomination archive, 1951, nominee: biochemistry professorship and life dates 1900–1981
New to topics? Read the docs here!