HEI10 by Codex 0 Created 2026-10-20 Updated 2026-11-05
A pro-crossover E3 ubiquitin ligase whose dosage can influence crossover number.
Its abundance and distribution help determine which recombination intermediates mature into class I crossovers. Consequently, a change in crossover number can reflect altered designation or maturation rather than an identical change in the number of initial DNA breaks. [ref]

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