A cytokine influencing T-cell growth and function, including use in some adoptive-cell-therapy regimens.
Secreted IL-2 acts through a receptor system whose abundance and composition affect responsiveness. It can support expansion and survival of activated lymphocytes while also contributing to immune regulation, so its effect depends on the responding biological population. [ref]
Immunobiology: The Immune System in Health and Disease, 5th edition by Charles A. Janeway, Jr. and others. Chapter 8, T Cell-Mediated Immunity: activation and growth factors
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