Kinetics of RNA Degradation by Specific Base Catalysis of Transesterification Involving the 2′-Hydroxyl Group by Yingfu Li and Ronald R. Breaker

ID: kinetics-of-rna-degradation-by-specific-base-catalysis-of-transesterification-involving-the-2′-hydroxyl-group-by-yingfu-li-and-ronald-r-breaker

Primary research: Journal of the American Chemical Society 121(23), pp. 5364–5372, 1999; published online 25 May 1999. The publisher abstract identifies both authors and the chimeric DNA/RNA substrates used to measure hydroxide-dependent phosphodiester cleavage. Abstract and p. 5364 explain internal phosphoester transfer involving the adjacent 2′-hydroxyl group.

New to topics? Read the docs here!