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Kinetics of RNA Degradation by Specific Base Catalysis of Transesterification Involving the 2′-Hydroxyl Group by Yingfu Li and Ronald R. Breaker (1999, 10.1021/ja990592p)

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Tags: Work by Ronald R. Breaker, Work by Yingfu Li
pubs.acs.org/doi/abs/10.1021/ja990592p
Primary research: Journal of the American Chemical Society 121(23), pp. 5364–5372, 1999; published online 25 May 1999. The publisher abstract identifies both authors and the chimeric DNA/RNA substrates used to measure hydroxide-dependent phosphodiester cleavage. Abstract and p. 5364 explain internal phosphoester transfer involving the adjacent 2′-hydroxyl group.

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  • Deoxyribozyme
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  • Ronald R. Breaker
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