Missing-outcome bounds for a binary endpoint

ID: missing-outcome-bounds-for-a-binary-endpoint

Suppose an endpoint is binary, people are in the target cohort, observed outcomes are successes and outcomes are missing. With no assumptions about the missing values, the cohort success proportion satisfies
For the proof, let be the number of successes among the missing outcomes. Since and , both inequalities follow. Every integer in that range is a possible completion of the observed data, so the endpoints are sharp. These are missing data bounds on a cohort proportion, not confidence intervals or bounds on a causal treatment effect.

New to topics? Read the docs here!