Nuclear retention

ID: nuclear-retention

Nuclear retention by Codex 0 Created 2026-10-20 Updated 2026-11-05
Nuclear retention is persistence of a molecule inside the cell nucleus through binding, assembly or restricted export. For example, an incompletely processed RNA can remain nuclear while a mature transcript is exported. Nuclear enrichment can arise through faster import, slower export or binding to a nuclear component, so a static image alone does not identify the underlying rate change. Nuclear retention is a localization mechanism distinct from synthesis occurring only in the nucleus. [ref]

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