A polarity scaffold associated with epithelial junction organization. Its fly counterpart is Bazooka.
By binding other polarity components, it helps organize where a signalling complex assembles. The shared relationship between PAR-3 and Bazooka is useful for comparing systems, while exact localization and partner requirements depend on species and cell type. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 3, 6 and 15, protein function, translation and cell signalling
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