Solution

ID: past-exam-of-the-mathematical-and-computational-biology-course-of-the-university-of-cambridge/2025/paper-1/4/c/solution

The deviance entries are for these fitted models. The completed values are
The likelihood-ratio test compares a model with one age coefficient against its restriction . Its small p-value, approximately , supports a positive age association under the assumed Gaussian linear mixed model. Refitting with maximum likelihood estimation is essential here: restricted maximum likelihood values from models with different fixed-effect design matrices cannot be compared by this likelihood-ratio test.

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